Selected Peer-Reviewed Publications

If you would like an electronic copy of a publication listed below, please email beacon@uci.edu

• Adams, J.N., Márquez, F., Larson, M.S., Janecek, J.T., Miranda, B., Noche, J.A., Taylor, L., Hollearn, M., McMillan, L., Keator, D., Head, E., Rissman, R., Yassa, M.A. (2023) Differential involvement of hippocampal subfields in the relationship between Alzheimer’s pathology and memory interference in older adults. Alzheimer’s and Dementia 15(2):e12419.
• Woo, C.C., Miranda, B., Sathishkumar, M., Dekhordi-Vakil, F., Yassa, M.A., Leon, M. (2023) Olfactory enrichment improves memory and modifies the uncinate fasciculus in older adults. Frontiers in Neuroscience 17. doi:10.3389/fnins.2023.1200448. 
• Adams, J.N., Chappel-Farley, M.G., Yaros, J.L., Taylor, L., Harris, A.L., Mikhail, A., McMillan, L., Keator, D.B., Yassa, M.A. (2023) Functional network structure supports resilience to memory deficits in cognitively normal older adults with amyloid-β pathology. Scientific Reports 13(1):13953. 
• Chwiesko, C., Janecek, J., Doering, S.S., Hollearn, M., McMillan, Vandekerckhove, J., Lee, M., Ratcliff, R., Yassa, M.A. Parsing Memory and Non-Memory Contributions to Age-Related Declines in Mnemonic Discrimination Performance: A Hierarchical Bayesian Diffusion Modeling Approach. Learning and Memory. In Press. 
• Kim, S., Adams, J., Chappel-Farley, M., Keator, D., Janecek, J., Taylor, L., Mikhail, A., Hollearn, M., McMillan, L., Rapp, P., Yassa, M.A. Examining the diagnostic value of the mnemonic discrimination task for classification of cognitive status and amyloid-beta positivity. Neuropsychologia. In Press. 
• Parker, D. M., Adams, J. N., Kim, S., McMillan, L., & Yassa, M. A.; Alzheimer’s Disease Neuroimaging Initiative. (2023, October 16). NODDI-derived measures of microstructural integrity in medial temporal lobe white matter pathways are associated with Alzheimer’s disease pathology and cognitive outcomes. bioRxiv. Advance online publication. 
• Chappel-Farley, M. G., Adams, J. N., Betzel, R. F., Janecek, J. C., Sattari, N. S., Berisha, D. E., Meza, N. J., Niknazar, H., Kim, S., Dave, A., Chen, I. Y., Lui, K. K., Neikrug, A. B., Benca, R. M., Yassa, M. A., & Mander, B. A. (2023, November 1). Medial temporal lobe functional network architecture supports sleep-related emotional memory processing in older adults. bioRxiv [Preprint]. Advance online publication.
• Rizvi, B., Sathishkumar, M., Kim, S., Márquez, F., Granger, S. J., Larson, M. S., Miranda, B. A., Hollearn, M. K., McMillan, L., Nan, B., Tustison, N. J., Lao, P. J., Brickman, A. M., Greenia, D., Corrada, M. M., Kawas, C. H., & Yassa, M. A. (2023). Posterior white matter hyperintensities are associated with reduced medial temporal lobe subregional integrity and long-term memory in older adults. NeuroImage. Clinical, 37, 103308.
• Chen, F. T., Soya, H., Yassa, M. A., Li, R. H., Chu, C. H., Chen, A. G., Hung, C. L., & Chang, Y. K. (2023). Effects of exercise types on white matter microstructure in late midlife adults: Preliminary results from a diffusion tensor imaging study. Frontiers in aging neuroscience, 14, 943992. 
• Granger, S. J., Colon-Perez, L., Larson, M. S., Bennett, I. J., Phelan, M., Keator, D. B., Janecek, J. T., Sathishkumar, M. T., Smith, A. P., McMillan, L., Greenia, D., Corrada, M. M., Kawas, C. H., & Yassa, M. A. (2023). Reduced structural connectivity of the medial temporal lobe including the perforant path is associated with aging and verbal memory impairment. Neurobiology of aging, 121, 119–128. 
• Parkin, G. M., Kim, S., Mikhail, A., Malhas, R., McMillan, L., Hollearn, M., Granger, D. A., Mapstone, M., Yassa, M. A., & Thomas, E. A. (2023). Associations between saliva and plasma cytokines in cognitively normal, older adults. Aging clinical and experimental research, 10.1007/s40520-022-02292-9. 
• Adams, J. N., Kim, S., Rizvi, B., Sathishkumar, M., Taylor, L., Harris, A. L., Mikhail, A., Keator, D. B., McMillan, L., & Yassa, M. A. (2022). Entorhinal-Hippocampal Circuit Integrity Is Related to Mnemonic Discrimination and Amyloid-β Pathology in Older Adults. Journal of Neuroscience, 42(46), 8742–8753. 
• Granger, S. J., Colon-Perez, L., Larson, M. S., Phelan, M., Keator, D. B., Janecek, J. T., Sathishkumar, M. T., Smith, A. P., McMillan, L., Greenia, D., Corrada, M. M., Kawas, C. H., & Yassa, M. A. (2022). Hippocampal dentate gyrus integrity revealed with ultrahigh resolution diffusion imaging predicts memory performance in older adults. Hippocampus, 32(9), 627–638. 
• Jutten, R.J., Rentz, D.M., Fu, J.F., Mayblyum, D.V., Amariglio, R.E., Buckley, R.F., Properzi, M.J., Maruff, P.T., Stark, C.E., Yassa, M.A., Johnson, K.A., Sperling, R.A., Papp, K.V. (2022) Monthly at-home computerized cognitive testing to detect diminished practice effects in preclinical Alzheimer’s disease. Frontiers in Aging Neuroscience 13:800126.
• Damrongthai, C., Kuwamizu, R., Suwabe, K., Ochi, G., Yamazaki, Y., Fukuie, T., Adachi, K., Yassa, M.A., Churdchomjan, W., Soya, H. (2021) Running boosts mood and executive function coinciding with bilateral prefrontal activation: An fNIRS study. Scientific Reports 11(1):22657. 
• Chappel-Farley, M., Mander, B.A., Nan, B., Grill, J., Yassa, M.A.*, Benca, R.* (2021) Symptoms of obstructive sleep apnea are associated with less frequent exercise and worse subjective cognitive function across adulthood. * Co-Corresponding Authors. Sleep 45(3)zsab240.
• Pagen, L., Smeets, T., Muller-Ehrenberg, L., Yassa, M.A., Verhey, F., Jacobs, H. (2021) Elevated noradrenaline levels are related to diminished practice effects in memory: A pilot study. Journal of Alzheimer’s Disease 80(4): 1675-1685.
• Nuño, M. M., & Gillen, D. L. (2021). Robust estimation in the nested case-control design under a misspecified covariate functional form. Statistics in medicine, 40(2), 299–311.
• Memel, M., Saffaroni, A., Cobigo, Y., Casaletto, K., Bettcher, B., Yassa, M.A., Elahi, F., Wolf, A., Rosen, H., Kramer, J. (2021) APOE moderates the effect of hippocampal blood flow on memory pattern separation in clinically normal older adults. Hippocampus doi: 10.1002/hipo.23327.
• Tustison, N.J., Cook, P.A., Holbrook, A.J., Johnson, H.J., Muschelli, J., Devanyi, G.A., Duda, J.T., Das, S., Cullen, N.C., Gillen, D.L., Yassa, M.A., Stone, J.R., Gee, J.C., Avants, B.B. for the Alzheimer’s Disease Neuroimaging Initiative (2021). ANTsX: A dynamic ecosystem for quantitative biological and medical imaging. Scientific Reports 11: 9068.
• Papp, K., Rentz. D.M., Maruff, P., Sun, C.K., Raman, R., Donohue, M., Schembri, A., Stark, C.E., Yassa, M.A., Wessels, A., Yaari, R., Holdridge, K., Aisen, P., Sperling, R. (2021) The computerized cognitive composite (C3) in an Alzheimer’s disease secondary prevention trial. The Journal of Prevention of Alzheimer’s Disease. 80(1):59-67.
• Holbrook AJ, Tustison NJ, Marquez F, Roberts J, Yassa MA, Gillen DL; Alzheimer’s Disease Neuroimaging Initiative (2020). Anterolateral entorhinal cortex thickness as a new biomarker for early detection of Alzheimer’s disease. Alzheimers Dement (Amst) 12(1):e12068. doi: 10.1002/dad2.12068.
• Riphagen JM, Schmiedek L, Gronenschild EHBM, Yassa MA, Priovoulos N, Sack AT, Verhey FRJ, Jacobs HIL (2020). Associations between pattern separation and hippocampal subfield structure and function vary along the lifespan. Scientific Reports 10(1):7572. doi: 10.1038/s41598-020-64595-z.
• Marquez, F., Yassa, M.A. (2019) Neuroimaging biomarkers for Alzheimer’s disease. Molecular Neurodegeneration 14(1):21.
• Tustison, N.J., Holbrook, A.J., Avants, B.B., Roberts, J.M., Cook, P.A., Reagh, Z.M., Stone, J.R., Gillen, D.L., Yassa, M.A. (2019) Longitudinal mapping of cortical thickness measurements: an ADNI-based evaluation study. Journal of Alzheimer’s Disease 71(1):165-183.
• Cruz, M., Gillen, D. L., Bender, M., & Ombao, H. (2019). Assessing health care interventions via an interrupted time series model: Study power and design considerations. Statistics in medicine, 38(10), 1734–1752.
• Nuño MM, Gillen DL. (2019) On Estimation in the Nested Case‐Control Design Under Non‐Proportional Hazards. Scandinavian Journal of Statistics 49(1): 265-286.
• Sinha N, Reagh ZM, Tustison NJ, Berg CN, Shaw A, Myers CE, Hill D, Yassa MA, Gluck MA. (2018) ABCA7 risk variant in healthy older African Americans is associated with a functionally isolated entorhinal cortex mediating deficient generalization of prior discrimination training. Hippocampus 10.1002/hipo.23042.
• Helfrich, R. F., Mander, B. A., Jagust, W. J., Knight, R. T., & Walker, M. P. (2018). Old Brains Come Uncoupled in Sleep: Slow Wave-Spindle Synchrony, Brain Atrophy, and Forgetting. Neuron, 97(1), 221–230.e4.
• Suwabe K, Byun K, Hyodo K, Reagh ZM, Roberts JM, Matsushita A, Saotome K, Ochi G, Fukuie T, Suzuki K, Sankai Y, Yassa MA, Soya H (2018) Reply to Gronwald et al.: Exercise intensity does indeed matter; maximal oxygen uptake is the gold-standard indicator. Proc Natl Acad Sci U S A 115(51):E11892-E11893.
• Suwabe K, Byun K, Hyodo K, Reagh ZM, Roberts JM, Matsushita A, Saotome K, Ochi G, Fukuie T, Suzuki K, Sankai Y, Yassa MA, Soya H. (2018) Rapid stimulation of human dentate gyrus function with acute mild exercise.. Proc Natl Acad Sci USA 115(41):10487-10492
• Reagh, Z.M., Noche, J.A., Tustison, M.J., Delisle, D., Murray, E.A., Yassa, M.A. (2018) Functional imbalance of anterolateral entorhinal cortex and hippocampal dentate/CA3 underlies age-related object pattern separation deficits. Neuron 97(5),1187-1198.e4.
• Trieu, T., Sajjadi, S. A., Kawas, C. H., Nelson, P. T., & Corrada, M. M. (2018). Risk factors of hippocampal sclerosis in the oldest old: The 90+ Study. Neurology, 91(19), e1788–e1798.
• Leal, S.L., Yassa, M.A. (2018) Integrating new data and examining clinical applications of pattern separation. Nature Neuroscience, 21, 163–173.
• Sinha, N., Berg, C. N., Tustison, N. J., Shaw, A., Hill, D., Yassa, M. A., & Gluck, M. A. (2018). APOE ε4 status in healthy older African Americans is associated with deficits in pattern separation and hippocampal hyperactivation. Neurobiology of aging 69:221-229.
• Reagh, Z.M., Yassa, M.A. (2017) Selective vulnerabilities and biomarkers in neurocognitive aging. F1000 reviews. 6(F1000 Faculty Rev):491.
• Suwabe, K., Hyodo, K., Byun, K.H., Ochi, G., Fukui, T., Shimizu, T., Kato, M., Yassa, M.A., Soya, H. (2017) Aerobic fitness associates with mnemonic discrimination as a mediator of physical activity effects: Evidence for memory flexibility in young adults. Scientific Reports. 7:5140.
• Leal, S.L., Noche, J.A., Murray, E.A., Yassa, M.A. (2017) Disruption of amygdala-entorhinal-hippocampal network in late life depression. Hippocampus 27(4):464-476.
• Sprecher, K. E., Koscik, R. L., Carlsson, C. M., Zetterberg, H., Blennow, K., Okonkwo, O. C., Sager, M. A., Asthana, S., Johnson, S. C., Benca, R. M., & Bendlin, B. B. (2017). Poor sleep is associated with CSF biomarkers of amyloid pathology in cognitively normal adults. Neurology, 89(5), 445–453.
• Bennett, I. J., Greenia, D. E., Maillard, P., Sajjadi, S. A., DeCarli, C., Corrada, M. M., & Kawas, C. H. (2017). Age-related white matter integrity differences in oldest-old without dementia. Neurobiology of aging, 56, 108–114.
• Mander, B. A., Zhu, A. H., Lindquist, J. R., Villeneuve, S., Rao, V., Lu, B., Saletin, J. M., Ancoli-Israel, S., Jagust, W. J., & Walker, M. P. (2017). White Matter Structure in Older Adults Moderates the Benefit of Sleep Spindles on Motor Memory Consolidation. The Journal of neuroscience, 37(48), 11675–11687.
• Leal, S.L., Noche, J.A., Murray, E.A., Yassa, M.A. (2016) Age-related individual variability in memory performance is associated with amygdala-hippocampal circuit function and emotional pattern separation. Neurobiology of Aging 49:9-19.
• Leal, S.L.*, Noche, J.A.*, Murray, E.A., Yassa, M.A. (2016) Positivity Effect Specific to Older Adults with Subclinical Memory Impairment. Learning and Memory 23: 415-421 * Co-first authors
• Reagh, Z.M., Ho, H.D., Leal, S.L., Noche, J.A., Chun, A., Murray, E.A., Yassa, M.A.(2016)  Greater loss of object than spatial mnemonic discrimination in aged adults. Hippocampus 26(4):417-22.
• Schwab, E., Yassa, M.A., Weiner, M., Vidal, R. (2016) Using Automatic HARDI Feature Selection, Registration, and Atlas Building to Characterize the Neuroanatomy of Aβ Pathology. Full length conference paper, CDMRI Workshop, MICCAI, Munich.DOI: 10.1007/978-3-319-28588-7_18.
• Leal, S.L., Yassa, M.A. (2015). The Aging Hippocampus: A Cross-Species Examination. In The Preservation of Memory. Psychology Press.
• Leal, S.L., Yassa, M.A. (2015) Neurocognitive aging and the hippocampus across species. Trends in Neurosci 38(12):800-12.
• Reagh, Z.M., Yassa, M.A (2014) Object and spatial mnemonic interference differentially engage lateral and medial entorhinal cortex in humans. Proc Natl Acad Sci U S A 111(40):E4264-73.
• Leal, S.L., Yassa, M.A. (2014) Effect of aging on mnemonic discrimination of emotional information. Behavioral Neuroscience 128(5):539-547.
• Roberts J.M., Ly, M., Murray, E., Yassa, M.A. (2014) Temporal discrimination deficits as a function of lag interference in older adults. Hippocampus 24(10):1189-96.
• Reagh, Z.M., Roberts, J.M., Ly, M., DiProspero, N., Murray, E., Yassa, M.A. (2013) Spatial discrimination deficits as a function of mnemonic interference in aged adults with and without memory impairment. Hippocampus 24(3):303-14.
• Schwab, E., Cetingul, E., Afsari, B., Yassa, M.A., Vidal, R. (2013) Rotation invariant features for HARDI. Information Processing in Medical Imaging (IPMI) 7917: 705-717.
• Ly, M., Murray, L., Yassa, M.A. (2013) Perceptual versus conceptual interference and pattern separation of verbal stimuli in young and older adults. Hippocampus 23(6):425-30.
• Leal, S., Yassa, M.A. (2013) Perturbations of Neural Circuitry in Aging, Mild Cognitive Impairment, and Alzheimer’s Disease. Ageing Research Reviews 12(3):823-31.
• Stark, S.M., Yassa, M.A., Lacy, J.W., Stark, C.E. (2013) A task to assess behavioral pattern separation (BPS) in humans: data from healthy aging and mild cognitive impairment. Neuropsychologia 51(12): 2442-2449.
• Bakker, A., Krauss, G., Albert, M.A., Speck, C.L., Jones, L.R., Stark, C.E., Yassa, M.A., Bassett, S.S., Shelton, A.L., Gallagher, M. (2012) Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment. Neuron 74, 467-474.
• Yassa, M.A. (2011) Searching for novel biomarkers using high-resolution diffusion tensor imaging. Journal of Alzheimer’s Disease 26(3): 297-305.
• Yassa, M.A. (2011) Searching for novel biomarkers using high-resolution diffusion tensor imaging. In J.W. Ashford, A. Rosen, M. Adamson, O. Sabri, S. Black, G. Frisoni, C. Jack, M. Weiner (Eds.) Handbooks of Alzheimer’s disease: Volume 2. Imaging the Alzheimer Brain. IOS Press, Amsterdam, The Netherlands. pp 547-555.
• Yassa, M.A., Stark, C.E. (2011) Pattern separation in the hippocampus. Trends in Neurosciences 34(10): 515-525.
• Yassa, M.A., Mattfeld, A.T., Stark, S.M., Stark, C.E.L. (2011) Age-related memory deficits linked to circuit-specific disruptions in the hippocampus. Proceedings of the National Academy of Sciences USA 108(21): 8873-8.
• Lacy, J.W., Yassa, M.A., Stark, S.M., Stark, C.E.L. (2011) Distinct pattern separation related transfer functions in human CA3/dentate and CA1 revealed using high-resolution fMRI and variable mnemonic similarity. Learning and Memory 18: 15-18.
• Yassa, M.A., Muftuler, L.T., Stark, C.E.L. (2010) Ultrahigh-resolution microstructural diffusion tensor imaging (msDTI) elucidates perforant path degradation in aged humans in vivo. Proceedings of the National Academy of Sciences U S A 107(28): 12687-91.
• Stark, S.M. Yassa, M.A., Stark, C.E.L. (2010) Individual differences in spatial pattern separation performance associated with healthy aging in humans. Learning and Memory 17(6):284-8.
• Yassa, M.A., Wu, J., Stark, S.M., Albert, M.S., Gallagher, M., Stark, C.E.L. (2010-11) Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults. Hippocampus 21:968-979.
• Yassa, M.A., Stark, S.M., Bakker, A., Albert, M.S., Gallagher, M., Stark, C.E.L. (2010) High-resolution functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic mild cognitive impairment. NeuroImage 51(3): 1242-1252.
• Gallagher M., Bakker A., Yassa M.A., Stark C.E.L. (2010) Bridging neurocognitive aging and disease modification: targeting functional mechanisms of impairment. Current Alzheimer’s Research 7(3):197-9.